Department of Medicine

Division of Hematology and Oncology

Vijay Reddy, M.D., Ph.D. Assistant Professor Division of Hematology / Oncology University of Florida Division of Hematology/Oncology P.O. Box 100277, College of Medicine Gainesville, Florida 32610-0277 Telephone/FAX: 352-392-3268, 352-392-2129

Training:

Clinical Activities:

Attending physician at Shands Hospital at the University of Florida in the Blood and Marrow Transplantation and hematological malignancies program.

Research Interests:

Involved in immunology, cancer and stem cell transplantation research. Focus is on Dendritic cells, immune reconstitution and cytokines after transplantation and vaccines treatment in leukemia.

Grant Awards:

• 12/1/05 – 06/30/09
  National Institute of Health
  Fred Hutchinson Cancer Research Center/Cellular Immunity to Aspergillus
  Goal is to study immunity to aspergillus infections in stem cell transplant recipients.
• 5/1/02 – 06/26/06
  Therakos
  A randomized single blind study of extracorporeal photoimmune therapy with UVADEX in conjunction with standard therapy compared to standard therapy alone for the treatment of skin manifestations in patients with steroid refractory or steroid dependent chronic graft-versus-host disease.
• 11/10/03 – 11/10/05
  Genzyme
  Pilot trial of two dose levels of thymoglobulin as part of a myeloablative-conditioning for a HLA identical matched related donor (MRD) stem cell transplantation (SCT) with cyclosporine (CsA) as posttransplant graft-versus-host disease (GvHD) prophylaxis.
• Current TBD
  Therakos
  A randomized, controlled, parallel group, multicenter study of Extracorporeal photoimmune therapy with UVADEX for the treatment of patients with newly diagnosed acute graft-versus-host disease.
• Current TBD
  National Marrow Donor Program (NMDP)
  Genzyme
  Immunoablative conditioning regimens using fludarabine, busulfan, and rabbit derived antithymocyte globulin (Thymoglobulin); or fludarabine with low dose total body irradiation allowing allogeneic stem cell support in patients with hematologic/oncologic diseases.
• 2004-2005
  Shands Stem Cell Laboratory Research and Development fund
  Dendritic cell adoptive immunotherapy for cancer and post transplant immune reconstitution.

Honors and Awards:

• 1986 – 1990 Graduate Student Fellowship, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, Canada
• 1987 Excellence in Research Award, Graduate Students Research Forum, Memorial University of Newfoundland, St. John’s, Canada
• 1992 Residents Research Award, Faculty of Medicine,
• Memorial University of Newfoundland, St. John’s, Canada
• 1993 American Society of Hematology Travel Award,
• 37th American Society of Hematology Meeting, Seattle, WA
• 2000 – 2001 College Investment Fund
• 2000 – 2002 UF Opportunity Fund
• 2004 American Society of Blood and Marrow Transplantation Travel Grant, 2004 Tandem Meetings, Orlando, FL

Representative Publications:

1. Reddy V, Meier-Kriesche H-U, Greene S, Schold JD, Wingard JR. Elevated levels of tumor necrosis factor-α (TNF) are associated with an increased risk of cytomegalovirus (CMV) infection after allogeneic hematopoietic stem cell transplantation (HSCT). Biology of Blood and Marrow Transplantation. 2005 Sep;11(9):698-705.
2. Seebach JD, Stussi G, Passweg JR, Lobierza Jr FR, Gajewski JL, Keating A, Goerner M, Rowlings PA, Tiberghien P, Elfenbein JG, Gale RP, van Rood JJ, Reddy V, Gluckman E, Bolwell BJ, Klumpp TR, Horowitz MM, Rindén O, Barrett AJ. ABO blood group barrier in allogeneic bone marrow revisited. Biology of Blood and Marrow Transplantation. 2005 Dec;11(12):1006-13
3. Reddy V, Winer AG, Eksioglu E, Meier-Kriesche H-U, Schold JD, Wingard JR. Interleukin-12 is associated with reduced relapse without increased incidence of graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation. 2005 Dec;11(12):1014-21
4. Ullmann, AJ, Lipton J, Vesole DH, Chandrasekhar P, Langston A, Tarantolo S, Greinix H, Azevedo W, Reddy V, Boparai N, Pedicone L, Patino H, Durrant S. Posaconazole versus Fluconazole for prophylaxis of Invasive Fungal Infections in Allogeneic hematopoietic stem cell transplant recipients with severe graft-versus-host disease. (under final review: New England Journal of Medicine).
5. Watts K, Tran-Son-Tay R, Reddy V, “The effects of ex vivo expansion on the differentiation of umbilical cord blood derived CD34+ cells” (In press: Journal of stem cells)
6. Watts K, Reddy V, Tran-Son-Tay R. “Rheologic properties of umbilical cord derived stem cells (submitted: Journal of Stem cells)