Hematology & Oncology
Division of Hematology and Oncology
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David Reisman, M.D, Ph.D. Associate Professor 1600 SW Archer Road- Box 100278 Gainesville, FL 32610 Email: David.Reisman@medicine.ufl.edu Lab Address: 1000 Archer Rd Cancer and Genetics Building Lab 275 D/E |
Dr. Reisman earned his BA at the University of California Berkeley and his M.D., Ph.D. at the University of Texas. He finished his residence, fellowship, and postdoctoral research work at the University of North Carolina. He matriculated to the University of Michigan in 2002 as an Assistant Professor of Medicine in the Hematology/Oncology division. He came to the University of Florida College Of Medicine in July of 2009 as an Associate Professor in the Division of Hematology/Oncology. His focus as a physician scientist is to identifying novel oncogenic targets and to develop new drugs to reverse their cancerigenic effects. Dr. Reisman’s focus is on thoracic cancer with an emphasis on lung cancer in particular BAC or bronchoaveolar carcinoma.
Training:
| Degree Program |
Institution | Field/Specialty |
| B.A. | University of California Berkeley | Biophysic |
| Ph.D | University of Texas | Molecular and Cell Biology |
| M.D. | University of Texas | Medicine |
| Residency | University of North Carolina | |
| Fellowship | University of North Carolina |
|
| Postdoctoral Research | University of North Carolina | Molecular biology of the SWI/SNF complex in cancer |
Clinical Interests:
Lung cancer and BAC treatment
Research Interests:
Studying the mechanism of BRG1 and BRM loss in cancer and how to restore the expression of these tumor suppressor proteins using small molecule inhibitors.
Investigate molecular defect underlying the development and progression of cancer.
Development of novel therapies which target the molecular defects underlying cancer.
The study of cancer stem cells and their role in cancer development.
Representative Publications:
- Reisman D., Sciarrotta, J., Weissman B., and Funkhouser W. The Expression of the SWI/SNF ATPase subunits BRG1 and BRM in normal human tissues. Applied Immunohistochemistry and Molecular Morphology. 2005 Mar; 13 (1):66-74.
- Glaros S., Cirrincione G., Muchardt C., Kleer C., Michael C., Reisman D. The reversible epigenetic silencing of BRM: implications for clinical targeted therapy Oncogene 2007 Oct 25;26(49):7058-66.
- Glaros S, Cirrincione GM, Palanca A, Metzger D, Reisman D. Targeted knockout of BRG1 potentiates lung cancer development. Cancer Res. 2008 May 15;68(10):3689-96.
- Rachel Wilson, Selina Glaros, Richard K. J. Brown, Claire Michael and David Reisman: Complete Radiographic Response of Primary Pulmonary Angiosarcomas Following Gemcitabine and Taxotere, Lung Cancer. 2008 Jul;61(1):131-6.
- Reisman D, Glaros S. and Thompson E.A. SWI/SNF and Cancer, 2009, Oncogene p1-16. 2009 Apr 9;28(14):1653-68.