Southwick Lab
 
Investigating Dynamic Remodeling of the Actin Cytoskeleton
 

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Please click over the author names to go to Pubmed record
   
1
Bubb MR, Yarmola EG, Gibson BG, Southwick FS Depolymerization of actin filaments by profilin. Effects of profilin on capping protein function.J Biol Chem. 2003 Jul 4; 278(27): 24629-35.
 
2
Falet H, Hoffmeister KM, Neujahr R, Italiano JE Jr, Stossel TP, Southwick FS, Hartwig JH. Importance of free actin filament barbed ends for Arp2/3 complex function in platelets and fibroblasts. Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16782-7.
 
3 Southwick FS, Li W, Zhang F, Zeile WL, Purich DL.  Actin-based endosome and phagosome rocketing in macrophages: activation by the secretagogue antagonists lanthanum and zinc. Cell Motil Cytoskeleton. 2003 Jan;54(1):41-55.
   
4 Dickinson RB, Southwick FS, Purich DL. A direct-transfer polymerization model explains how the multiple profilin-binding sites in the actoclampin motor promote rapid actin-based motility. Arch Biochem Biophys. 2002 Oct 15;406(2):296-301.
   
5 Zhang F, Southwick FS, Purich DL. Actin-based phagosome motility. Cell Motil Cytoskeleton. 2002 Oct;53(2):81-8.
   
6 Tchernev VT, Mansfield TA, Giot L, Kumar AM, Nandabalan K, Li Y, Mishra VS, Detter JC, Rothberg JM, Wallace MR, Southwick FS, Kingsmore SF. The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins. Mol Med. 2002 Jan;8(1):56-64.
   
7 Witke W, Li W, Kwiatkowski DJ, Southwick FS.  Comparisons of CapG and gelsolin-null macrophages: demonstration of a unique role for CapG in receptor-mediated ruffling, phagocytosis, and vesicle rocketing. J Cell Biol. 2001 Aug 20;154(4):775-84.
   
8 Southwick FS.  Gelsolin and ADF/cofilin enhance the actin dynamics of motile cells. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):6936-8.
   
9 Southwick FS, Adamson ED, Purich DL.  Shigella actin-based motility in the presence of truncated vinculin. Cell Motil Cytoskeleton. 2000 Apr;45(4):272-8.
   
10 Kang F, Purich DL, Southwick FS.  Profilin promotes barbed-end actin filament assembly without lowering the critical concentration. J Biol Chem. 1999 Dec 24;274(52):36963-72.
   
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