Nephrology, Hypertension & Renal Transplantation
Nephrology, Hypertension & Renal Transplantation
Research
The division has an extensive research program in the clinical and basic sciences that is supported largely through extramural research funds.
Clinical studies are investigating a variety of aspects of renal disease. The AASK study is a multi-centered, randomized, controlled study, funded by the NIH, designed to address the optimal methods of treating African-Americans with hypertensive nephrosclerosis. Other studies involve the role of uric acid in mediating hypertension and investigations into the cause of increase risk of cardiovascular disease in both end-stage kidney disease patients, patients with chronic kidney disease, and in patients with Lupus. In addition, studies are ongoing in the division to address the prevention of rejection in renal transplant patients. Finally, we are continuing our long tradition of participating in several multicenter clinical studies.
A number of basic science laboratories in the Division are studying a variety of features of normal and abnormal renal function. These include renal development, regulation of potassium transport, response to acid-base abnormalities, control of renal function by hormones, second-messenger regulation of renal function, regulation of renal ATPases, the molecular biology of ion transport, sex hormone regulation of renal function, and renal protection against oxidant acute renal failure.
Fellows are encouraged to participate in a project of their choosing during the second and subsequent years of their fellowship