Pulmonary, Critical Care, and Sleep Medicine
Pulmonary, Critical Care, and Sleep Medicine Faculty
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Mark L. Brantly, M.D. Professor of Medicine, Molecular Genetics and Microbiology Alpha One Foundation Research Professor Pulmonary, Critical Care, and Sleep Medicine University of Florida College of Medicine JHMHC PO Box 100225 Gainesville, FL 32610 Phone 352-392-7861 FAX 352-392-7088 Email id: brantml@medicine.ufl.edu |
Educational Background
- 1979 M.D. University of Florida, Gainesville
- 1976 B.S. Florida State University, Tallahassee, Florida
Clinical Interests
- - Alpha 1 Antitrypsin Deficiency
- - Chronic Obstructive Pulmonary Disease
Research Interests
- - Role of Inflammation in Alpha-1 Antitrypsin Deficiency
- - Chronic Obstructive Pulmonary Disease
Professional Societies
- American Thoracic Association
- American Society of Cell Biology
Publications (2004 onwards)
- M. Brantly, J. Wittes, C. Vogelmeier, R. Hubbard, G. Fells, and R. Crystal. Use of a Highly Purified a1-Antitrypsin Standard to Establish Ranges for the Common Normal and Deficient a1-Antitrypsin Phenotypes. Chest 1991 Sept;100:703-708.
- Flotte TR, Brantly ML, Spencer LT, Byrne BJ, Spencer CT, Baker DJ, Humphries M. Phase I trial of intramuscular injection of a recombinant adeno-associated virus alpha 1-antitrypsin (rAAV2-CB-hAAT) gene vector to AAT-deficient adults. Human Gene Therapy 2004 Jan; 15:93-128.
- Strange, C., Dickson, R., Carter, C., Carpenter, M.J., Holladay, B., Lundquist, R., Brantly, M.L. Genetic Testing for Alpha1-Antitrypsin Deficiency. Genetic Testing for Alpha1-Antitrypsin Deficiency. In press Genetics in Medicine 2004.
For a complete list of the publications,
Visit Pubmed, US National Library of Medicine (NLM)
Patents
Increased Expression of Alpha-1-Antitrypsin in Expression Vectors through the inclusion of Intron II. Patent Serial Number 08/060,925
Honors and Awards
1995 Alpha1 National Association Award
1998 Alpha1 Foundation Research Professorship