Pulmonary, Critical Care, and Sleep Medicine

Pulmonary, Critical Care, and Sleep Medicine Faculty

J.M. Patel, M.D. J.M. Patel, M.D.
Professor of Medicine
Pulmonary, Critical Care, and Sleep Medicine
University of Florida College of Medicine

Box 100225
University of Florida Health Science Center
Gainesville, Florida 32610-0225
Phone (352) 392-2666 or 376-1611 x6448
Fax (352) 379-7421
Email id: pateljm@medicine.ufl.edu


Educational Background

  • 1973 PhD Biochemistry, Marathwada University, Aurangabad
  • 1971 MSc Biochemistry, Marathwada University, Aurangabad

Research Interests

  • - Development of a rat model of lung transplantation
  • - Biology and toxicology of nitric oxide (NO)
  • - Regulation of lung endothelial cell NO synthase (eNOS)
  • - Pulmonary system toxicology of drugs and environmental chemicals
  • - Role of Thioredoxin in Lung Allograft Inju

Professional Societies

  • Society of Toxicology
  • Society for Free Radical Biology and Medicine
  • Nitric Oxide Society
  • American Society for Pharmacology & Experimental Therapeutics

Grants Awarded

Florida Department of Health: Co-Principal Investigator “Tobacco Smoke-Induced Cell Injury in Lung Compartments” 2004-2005

NIH: Principal Investigator “NO Toxicity: Redox Regulation of Lung Cell Thioredoxin" 2001 - 2006

NIH: Principal Investigator “Calreticulin Regulation of Lung Endothelial Cell NOS" 2001 - 2005

VA Merit Review: Principal Investigator “Mechanism of Angiotensin IV-Mediated Regulation of Lung Endothelium NOS” 2000 – 2005

NIH: Co-Principal Investigator “Short Term Research Training for Minority Students” 1999-2004

Publications (2004 onwards)

  • “Autoinhibitory Doamin Fragment of Endothelial NOS Enhances Pulmonary Artery Vasorelaxation by NO/cGMP Pathway”.Hanbo Hu, M. Xin, L.L. Belayev, J.L. Zhang, E.R. Block, and J.M. Patel. Am. J. Physdiol Lung Cell Mol. Physiol.286: L1066-L1074, 2004.
  • “Nitric Oxide-Modulated Marker Gene Expression of Signal Transduction Pathways in Lung Endothelial Cells” Liuzhe Li, J.L. Zhang, E.R. Block, and J.M. Patel. Nitric Oxide. In Press.
  • “Nitric Oxide-Induced Persistent Inhibition and Nitrosylation of Active Site Cysteine Residues of Mitochondrial Cytochrome c Oxidase in Lung Endothelial Cells”. J.L. Zhang, Bilian Jin, Liuzhe Li, E.R. Block, and J.M. Patel. Am.J.Physiol Cell Physiol. In Press

For a complete list of the publications,
Visit Pubmed, US National Library of Medicine (NLM)

Honors and Awards

2003 - 2005 University of Florida Research Foundation (UFRF) Professorship Award

1995-2000 Member Alcohol and Toxicology Study Section, NIH

1995-1998 Member VA Merit Review Subcommittee for Respiration & Pulmonary Disease

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